盛文龙个人信息
姓 名 | 盛文龙 | 性 别 | 男 |  |
籍 贯 | 山东莒县 | 出生年月 | 1988.12 | |
职 称 | 副研究员 | 政治面貌 | 中共党员 | |
专 业 | 生物与医药 | 职 务 | 无 | |
导师类别 | 硕导 | 学历、学位 | 研究生、博士 | |
课 题 组 | 药物筛选研究室 | |||
工作信息 | 手机：15618694162； 邮箱：shengwenlong@sdas.org | |||
隶属单位 | 山东省科学院生物研究所 | |||
通讯地点 | 济南市历城区经十东路28789号 | |||
学习、工作简历： 2020.01至今 皇冠（山东省科学院）生物研究所 药物筛选研究室 副研究员 2019.03至今 山东省科技厅科技合作处（借调） 2016.08~2019.03 山东省科学院生物研究所 药物筛选研究室 助理研究员 2011.09~2016.06 复旦大学 生命科学学院 神经生物学 硕博连读 导师：杨雄里院士 2007.09~2011.07 山东轻工业学院 食品与生物工程学院 生物技术 | ||||
主要研究方向：1. 视网膜信息处理的神经机制及分子生物学基础；2. 荧光探针应用研究 | ||||
课题：
论文： 1.A coumarin-based fluorescent probe for Hg2+ and its application in living cells and zebrafish. Luminescence. 2020;1-6.（IF=1.691, 共同通讯作者） 2.A new phenylsulfonamide-based Golgi-targeting fluorescent probe for H2S and its bioimaging applications in living cells and zebrafish. Chemical Communications. 2020, 56, 4086-4089.（IF=6.164, 共同通讯作者） 3.A simple p-methylaminophenylether-based fluorescent probe for detecting native hypochlorous acid in live cells and zebrafish. Dyes and Pigments. 177 (2020) 108310. （IF=4.018, 共同通讯作者） 4.A novel highly selective ratiometric fluorescent probe with large emission shift for detecting mercury ions in living cells and zebrafish. Dyes and Pigments. 177 (2020) 108290. （IF=4.018, 共同通讯作者） 5.A Simple Long-wavelength Fluorescent Probe for Simultaneous Discrimination of Cysteine/Homocysteine and Glutathione/Hydrogen Sulfide with Two Separated Fluorescence Emission Channels by Single Wavelength Excitation. Anal Sci. 2020 Feb 10;36(2):255-262. （IF=1.618, 共同通讯作者） 6.A highly specific Golgi-targetable fluorescent probe for tracking cysteine generation during the Golgi stress response. Sensors & Actuators: B. Chemical 310 (2020) 127820. （IF=6.393, 共同通讯作者） 7.Visualization of cysteine level during Golgi stress with a novel targeting highly specific fluorescent probe. Chemical Communications. 2020, 56, 1807-1810（IF=6.164, 共同通讯作者） 8.Rational Design of a Targetable Fluorescent Probe for Visualizing H2S Production under Golgi Stress Response Elicited by Monensin. Anal. Chem. 2020, 92, 1883−1889.（IF=6.350, 共同通讯作者） 9.A novel Pd2+-free highly selective and ultrasensitive fluorescent probe for detecting CO-releasing molecule-2 in live cells and zebrafish. Dyes and Pigments 174 (2020) 108040. （IF=4.018, 共同通讯作者） 10.A highly sensitive rapid-response fluorescent probe for specifically tracking endogenous labile Fe2+ living cells and zebrafish. Dyes and Pigments 174 (2020) 108065. （IF=4.018, 共同通讯作者） 11.Development of a ratiometric fluorescent probe with a large emission shift for imaging ONOO- in live cells and zebrafish. Dyes and Pigments 173 (2020) 107942. （IF=4.018, 共同通讯作者） 12.A novel highly selective fluorescent probe for imaging endogenous hypobromous acid in living cells and zebrafish. Sensors & Actuators: B. Chemical 305 (2020) 127460. （IF=6.393, 共同通讯作者） 13.Cellular localization of melatonin receptor Mel1b in pigeon retina. Neuropeptides 78 (2019) 101974. （IF=2.407, 第一作者、通讯作者.） 14.Rational design of a hepatoma-specific fluorescent probe for HOCl and its bioimaging applications in living HepG2 cells. Anal. Chem., 2019, 91, 2163−2168.（IF=6.350, 共同通讯作者） 15.A carbonothioate-based far-red fluorescent probe for the specific detection of mercury ions in living cells and zebrafish. Analyst, 2019, 144, 1426–1432.（IF=4.019, 共同通讯作者） 16.Dichlororesorufin-Based Colorimetric and Fluorescent Probe for Ultrasensitive Detection of Mercury Ions in Living Cells and Zebrafish. Ind. Eng. Chem. Res., 2019, 58, 11−17.（IF=3.375, 共同通讯作者） 17.A metal-free near-infrared fluorescent probe for tracking the glucose-induced fluctuations of carbon monoxide in living cells and zebrafish. Sensors & Actuators: B. Chemical 291 (2019) 329–336. （IF=6.393, 共同通讯作者） 18.A long-wavelength ultrasensitive colorimetric fluorescent probe for carbon monoxide detection in living cells. Photochem. Photobiol. Sci., 2019, 18, 1851–1857. （IF=2.408, 共同通讯作者） 19.A highly specific and ultrasensitive p-aminophenylether-based fluorescent probe for imaging native HOCl in live cells and zebrafish. Analytica Chimica Acta, 2019, 1052, 131-136. （IF=5.256, 共同通讯作者） 20.Dicyanoisophorone-Derived Near-Infrared Fluorescent Probe for Ultrasensitive Detection of Peroxynitrite in Living Cells and Zebrafish. Ind. Eng. Chem. Res. 2019, 58, 19778−19784. （IF=3.375, 共同通讯作者） 21.Chemical constituents from Alismatis Rhizoma and their anti-inflammatory activities in vitro and in vivo. Bioorganic Chemistry 92 (2019) 103226. （IF=3.926, 共同第一作者） 22.A novel hepatoma-specific fluorescent probe for imaging endogenous peroxynitrite in live HepG2 cells. Sensors & Actuators: B. Chemical 289 (2019) 124–130. （IF=6.393, 共同通讯作者） 23.A water-soluble and highly specific fluorescent probe with large stokes shift for imaging basal HOCl in living cells and zebrafish. Sensors & Actuators: B. Chemical. 291 (2019) 243–249. （IF=6.393, 共同通讯作者） 24.Novel Dimethylhydrazine-Derived Spirolactam Fluorescent Chemodosimeter for Tracing Basal Peroxynitrite in Live Cells and Zebrafish. J. Agric. Food Chem. 2019, 67, 6407−6413. （IF=3.571, 共同通讯作者） 25.Development of a concise rhodamine-formylhydrazine type fluorescent probe for highly specific and ultrasensitive tracing of basal HOCl in live cells and zebrafish. ACS Sens. 2019 4(8):2156-2163. （IF=6.944, 共同通讯作者） 26.A highly selective and sensitive red-emitting fluorescent probe for visualization of endogenous peroxynitrite in living cells and zebrafish. Analyst. 2019, 144, 3442–3449. （IF=4.019, 共同通讯作者） 27.A water-soluble and highly specific fluorescent probe for imaging thiophenols in living cells and zebrafish. New J. Chem., 2019, 43, 6746—6752. （IF=3.069, 共同通讯作者） 28.A novel water-soluble fluorescent probe with ultra-sensitivity over a wider pH range and its application for differentiating cancer cells from normal cells. Analyst, 2019, 144, 6975. （IF=4.019, 共同通讯作者） 29.A novel ratiometric fluorescent probe for highly sensitive and selective detection of peroxynitrite and its application for tracing endogenous peroxynitrite in live cells. Anal.Methods, 2019, 11, 5699. （IF=2.378, 共同通讯作者） 30.A simple highly specific fluorescent probe for simultaneous discrimination of cysteine/homocysteine and glutathione/hydrogen sulfide in living cells and zebrafish using two separated fluorescence channels under single wavelength excitation. Analyst, 2019, 144, 4258–4265. （IF=4.019, 共同通讯作者） 31.A novel highly sensitive fluorescent probe for bioimaging biothiols and its applications in distinguishing cancer cells from normal cells. Analyst, 2019, 144, 7010. （IF=4.019, 共同通讯作者） 32.A novel hexahydropyridazin-modified rhodamine fluorescent probe for tracing endogenous/exogenous peroxynitrite in live cells and zebrafish. Dyes and Pigments 170 (2019) 107573. （IF=4.018, 共同通讯作者） 33.Novel carbohydrate modified berberine derivatives: synthesis and in vitro anti-diabetic investigation. Med. Chem. Commun., 2019, 10, 598. （IF=2.394, 共同第一作者） 34.Co-expression of two subtypes of melatonin receptor on rat M1-type intrinsically photosensitive retinal ganglion cells. PLoS One (2015) 10:e0117967. （IF=2.776, 第一作者） 35.Two novel non-holostane type glycosides from the viscera of sea cucumber Apostichopus japonicas. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH. 2019.1576643. （IF=1.170，第3/8位） 36.TWO NOVEL HOLOSTANE-TYPE GLYCOSIDES FROM THE VISCERA OF SEA CUCUMBER APOSTICHOPUS JAPONICUS WITH ANTITUMOR ACTIVITIES. Rev. Roum. Chim., 2019, 64(4), 353-359. （IF=0.395，第3/8位） 37.Activation of BDNF-TrkB signaling pathway-regulated brain inflammation in pentylenetetrazole-induced seizures in zebrafish. Fish and Shellfish Immunology 83 (2018) 26–36. （IF=3.298，第2/6位） 38. Synergistic effects of Pb and repeated heat pulse on developmental neurotoxicity in zebrafish. Ecotoxicology and Environmental Safety 172 (2019) 460–470. （IF=4.527，第4/6位） 39.A highly specific and sensitive ratiometric fluorescent probe for carbon monoxide and its bioimaging applications. New J.Chem., 2018, 42, 14417. （IF=3.069，第4/8位） 40.Temporal Neuromodulation of Retinal Ganglion Cells by Low-Frequency Focused Ultrasound Stimulation. IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, (2018) 26 (5). （IF=3.478，第4/12位） 41.RdgB2 is required for dim-light input into intrinsically photosensitive retinal ganglion cells. MBoC (2015) 26 3671-3678. （IF=3.905，第5/9位） 42.Signalling mechanism for somatostatin receptor 5-mediated suppression of AMPA responses in rat retinal ganglion cells. Neuropharmacology 107 (2016) 215e226. （IF=4.367，第2/6位） 43.Orexin-A differentially modulates AMPA-preferring responses of ganglion cells and amacrine cells in rat retina. Neuropharmacology 93 (2015) 80-93. （IF=4.367，第6/9位） 44.Effects of streptozotocin on pancreatic islet β-cell apoptosis and glucose metabolism in zebrafish larvae. 2020, Fish Physiol Biochem. （第4/8位） 专利： 1. 一种非海参烷型海参皂苷及其制备方法与应用，ZL201811012488.4，第8/8位。 2. 一种三氮唑糖修饰的小檗碱盐衍生物及其制备方法和用途，ZL201810711484.9，第4/5位。 3. 利用鳕鱼内脏制备高纯度海产多不饱和脂肪酸磷脂的方法，ZL2016111466659，第10/10位。 4. 一种用于冷冻组织切片中固定斑马鱼体位的装置，ZL201720082969.7，第7/7位。 5. 一种斑马鱼老年疾呆模型的建立方法及应用，ZL 201810724850.4，第6/8位。 | ||||
获奖： 无 | ||||
人才称号和荣誉： 2019年度山东省科学院生物研究所所嘉奖 2018年度山东省科学院院嘉奖 2017年度山东省科学院院嘉奖 | ||||
社会兼职：济宁医学院兼职讲师 | ||||
